![]() ![]() Isaac Bogoch, an infectious diseases physician and member of Ontario's COVID-19 vaccine task force. "We can assure everyone that Health Canada will, every step of the way, put the health of Canadians first and foremost around any decisions we make around the distribution of the vaccine," Trudeau said.Ī suspension of the vaccine in Canada would strike a blow to the country's vaccination campaign as it contends with a third wave, said Dr. With 10 million on order, Prime Minister Justin Trudeau said Canadian officials are closely monitoring the decision by U.S. The first doses of the Johnson & Johnson vaccine, which has been approved for use in Canada, are expected to be shipped here later this month. Ultimately, she said, "we may see tailored recommendations about Johnson & Johnson use for only low-risk groups if it does turn out to be related to the vaccine." What does this mean for Canada? Canada confirms 1st case of rare blood clot after AstraZeneca COVID-19 vaccineĪngela Rasmussen, a virologist at Georgetown University's Center for Global Health Science and Security in Washington, said there appear to be similarities between the blood clotting cases linked to the two vaccines but "cautioned it's still too early to jump to conclusions.".Second Opinion Why restricting AstraZeneca vaccines in Canada means balancing 'vaccine risk vs. Quebec's health minister said the woman is recovering at home. On Tuesday, Canada reported its first case of the clotting condition linked to the AstraZeneca vaccine. There have been no reports of any post-vaccination clots in people who have received the Pfizer or Moderna shots, which are based on mRNA technology, Marks said.Ĭanada's vaccine advisory committee recommended the suspension of the AstraZeneca vaccine for people under 55, following reports of rare but potentially fatal blood clots in Europe. Both are non-replicating viral vector vaccines, which use a modified adenovirus to deliver genetic instructions for a key coronavirus protein needed to protect against COVID-19. Marks said he believes there is a "similar mechanism" leading to the clots in the case of Johnson & Johnson and the AstraZeneca-Oxford vaccine. Are these the same kind of clots seen with AstraZeneca? But some people produce antibodies against the complex, leading to a clotting reaction. Heparin binds to a protein that forms a compound, known as a complex. When platelets are activated, they change from being round to spiny in order to stimulate blood clots. This adverse reaction appears to have similarities to a well-known condition called heparin-induced thrombocytopenia (HIT), where the blood thinner heparin paradoxically triggers the formation of an antibody that directly activates platelets. That immune response leads to activation of the platelets and extremely rare blood clots." ![]() The leading hypothesis, he said, is "this is an immune response that occurs very, very rarely after some people receive the vaccine. Peter Marks, director of the Center for Biologics Evaluation and Research at the FDA. "We don't have a definitive probable cause," Dr. federal distribution channels, including mass vaccination sites, will pause the use of the J&J shot, and states and other providers are expected to follow. ![]() More than 6.8 million doses of the J&J vaccine have been administered in the U.S. Janet Woodcock, the acting commissioner of the FDA, stressed in a briefing Tuesday that the potential risks remain small and that the decision was made "out of an abundance of caution." It isn't yet known how the clotting may have contributed.ĭr. One person died, and another patient is in critical condition. The clots occurred in veins that drain blood from the brain and occurred together with low platelets. In the U.S., the only country using the vaccine, all six cases were among women between the ages of 18 and 48, and symptoms occurred six to 13 days after vaccination. to make this decision, and what it could mean for Canada. Here's what we know about what led the U.S. Centers for Disease Control and Prevention and the Food and Drug Administration (FDA) said in a joint statement they are investigating blood clots in six women in the days after vaccination, in combination with reduced platelet counts.Ĭanada has approved the vaccine but hasn't yet received any doses. recommended putting on hold the use of the single-dose Johnson & Johnson COVID-19 vaccine. ![]()
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